METRO FREE Tuesday, November 3, 2009 HELP METRO HELP THE ENVIRONMENT. RECYCLE THIS NEWSPAPER TODAY INSIDE TODAY See Page 3 Your chance to vote in the Metro Photo Challenge See Page 15 We have 2,000 pairs of tickets for 7UPs Christmas On Ice... PLUS REALLY RICH: Barry Fitzgerald and Ronan Carroll jump for joy as they collect their share of Fridays 8.5million Lotto jackpot at the National Lottery offices in Dublin. They are members of the 20-strong syndicate at KennCo Underwriting in Rathfarnham which won with a 20 Quick Pick ticket Picture: Collins ScientiStS in Dublin have discov- ered a new drug they claim can kill leukaemia, it was revealed yesterday. Researchers maintain the drug, PBOX-15, can even destroy the can- cerous cells in adult patients with a poor prognosis and who have shown resistance to other treatments. the groundbreaking study was car- ried out by academics at trinity col- lege Dublin, in partnership with Uni- versity of Sienna, italy, and is published in the renowned interna- tional journal cancer Research. Professor Mark Lawler, of trinitys school of medicine, said it could be another three to five years before the drug is used as a life-saving treat- ment. We are still at an early stage, he said. now we have to move it on to see if there are any side effects and bring it forward as a potential therapy for patients. But its very exciting. We want to give hope to cancer patients. Prof Lawler, lead investigator on the study, revealed PBOX-15 attacked and broke down the skeleton in leu- kaemia cells in samples given by pa- tients. it was also successful when used in the treatment of chronic lymphocytic leukaemia (cLL), a type of cancer of the blood and bone marrow the most common leukaemia in adults in the western world. Latest data from the national can- cer Registry showed 114 new cases of cLL were diagnosed in ireland in 2007. the trinity researchers said PBOX-15 was more effective than the current medication, fludarabine, and also killed cLL cells resistant to other treatments. John Mccormack, of the irish can- cer Society, said the findings of the study had to be brought from the lab- oratory to the bedside. the findings that are being pub- lished today emphasise the potential for basic science discoveries to trans- late to clinical benefit, he said. BY SARAH STACK Trinity find drug that can kill off leukaemia Alex lets off some steam See Page 6 Full story: Page 5 index.html2.html3.html4.html5.html6.html7.html8.html9.html10.html11.html12.html13.html14.html15.html16.html17.html18.html19.html20.html21.html22.html23.html24.html25.html26.html27.html